Prescriber variation in potentially inappropriate prescribing in older populations in Ireland

BMC Primary Care

Table 2 Multilevel logistic regression adjusted odds ratios (95% CIs) for patients receiving at least one potentially inappropriate indicator

Variable	Model 1 random intercept patient level variables	Model 2 random intercept patient and GP level variables	Model 3 random slope patient and GP level variables
Variable	OR* (95% CIs)	OR* (95% CIs)	OR* (95% CIs)
Patient level fixed effects
*Gender*
Male	1	1	1
Female	0.92 (0.90, 0.93)	0.92 (0.90, 0.93)	0.92 (0.91, 0.93) 1
*Age*
70-74 years	1	1	10,(0.95)
≥ 75 years	0.95 (0.93, 0.97)	0.95 (0.93, 0.97)	0.95 (0.93, 0.96)
*No of different repeat drug classes*
0	1	1	1
1	2.00 (1.83, 2.18)	2.00 (1.83, 2.18)	1.43(1.43, 1.44) †
2	3.98 (3.69, 4.30)	3.98 (3.68, 4.30)
3	6.31 (5.87, 6.79)	6.31 (5.86, 6.78)
4	8.81 (8.20, 9.46)	8.81 (8.20, 9.45)
5	12.79 (11.92, 13.72)	12.78 (11.91, 13.71)
6	17.39 (16.21, 18.65)	17.38 (16.20, 18.64)
7	23.22 (21.65, 24.92)	23.21 (21.63, 24.90)
8	30.15 (28.09, 32.37)	30.13 (28.07, 32.35)
9	38.89 (36.19, 41.79)	38.86 (36.17, 41.76)
≥10	71.77 (67.00, 76.87)	71.71 (66.95, 76.81)
GP level fixed effects ^‡
*Gender* ^§
Male	-	1	1
Female	-	0.94 (0 .91, 0.97)	0.94 (0.91, 0.97)
*Area of residence*
Urban	-	1	1
Rural	-	0.98 (0.95, 1.01)	0.98 (0.94, 1.01)
*Deprivation*
Deprivation score (centred)	-	1.00 (0.99, 1.01)	1.00 (0.99, 1.01)

*OR = odds ratio.
^†The number of different repeat drug classes was treated as a continuous variable (created 10 dummy variables and the coefficients show an approximately linear increase).
^‡GP level data was unavailable for 108 (5%) GPs with 6,906 (2%) patients.
§GP gender was missing for 22 (1%) GPs with 2,578 (0.76%) patients.

ISSN: 2731-4553