Table 3 Change in observed outcome as a function of time
Primary outcome | Change per unit per month (linear), or change in odds ratio per month (binary categories) | (95% Confidence Interval) | P Value |
|---|---|---|---|
ACR | −6.75 | −10.98, −2.52 | 0.002 |
Secondary outcomes | |||
Estimated GFR | −0.34 | −0.55, −0.12 | 0.002 |
5-year absolute cardiovascular risk | −0.24 | −0.40, −0.09 | 0.002 |
“Intermediary” secondary outcomes - participant | |||
Systolic blood pressure (mmHg) | −1.65 | −2.02, −1.28 | <0.01 |
Diastolic blood pressure (mmHg) | −1.07 | −1.33, −0.81 | <0.001 |
Serum total cholesterol (mmol/L) | −0.05 | −0.08, −0.02 | 0.002 |
HbA1c (%) | −0.09 | −0.13, −0.06 | <0.001 |
BMI (kg/m2) | −0.06 | -.13, −0.008 | 0.08 |
Active smoking (odds ratio) | 0.69 | 0.54, 0.88 | 0.003 |
Self-management | |||
Overall score (scale 0 to 104) | 1.11 | 0.72, 1.50 | <0.001 |
Knowledge of medications (scale 0 to 8) | 0.17 | 0.12, 0.22 | <0.001 |
Knowledge of condition (scale 0 to 8) | 0.14 | 0.10, 0.18 | <0.001 |
Medication adherence (scale 0 to 8) | 0.05 | 0.001, 0.09 | 0.044 |
Healthy lifestyle (scale 0 to 8) | 0.06 | 0.02, 0.11 | 0.005 |
“Intermediary” secondary outcomes - provider | |||
Prescribed aspirin (odds ratio) | 1.61 | 1.23, 2.11 | <0.001 |
Prescribed ACEi/ARB (odds ratio) | 1.97 | 1.04, 3.72 | 0.037 |
Prescribed HMG-CoA reductase inhibitors (odds ratio) | 1.26 | 1.08, 1.46 | 0.003 |
Number of prescribed anti-hypertensives | 0.05 | 0.03, 0.07 | <0.001 |