Table 3 Chronic respiratory questionnaire subscale score, pulmonary function and 6-minute walking test differences from baseline to 3 and 12 months

−0.3 (−0.9-0.2)

0.09 (−0.5-0.6)

0.4 (−0.1-0.9)

0.02 (−0.6-0.6)

0.3 (−0.3-0.9)

0.3 (−0.3-0.9)

−0.4 (−1.3-0.5)

0.3 (−0.5-1.1)

0.7 (−0.1-1.5)

−0.3 (−1.8-1.1)

0.4 (−0.9-1.8)

0.8 (−0.6-2.1)

0.8 (0.05-1.5)*

0.3 (−0.4-0.9)

−0.5 (−1.2-0.2)

0.5 (−0.2-1.1)

0.1 (−0.5-0.8)

−0.3 (−0.9-0.3)

0.2 (−0.6-0.9)

0.3 (−0.5-1.1)

0.1 (−0.6-0.9)

0.5 (−0.6-1.6)

0.7 (−0.3-1,8)

0.3 (−0.8-1.3)

2.05 (−3.7-7.8)

−0.9 (−6.4-4.5)

−2.9 (−8.6-2.6)

1.6 (−5.2-8.4)

−2.4 (−8.9-4.1)

−3.9 (−10.7-2.7)

−0.9 (−6.8-5.04)

−2.9 (−8.6-2.7)

−2.05 (−7.8-3.7)

0.07 (−1.8-1.9)

−0.9 (−2.8-0.9)

−1.04 (−2.9-0.8)

−1.4 (−6.1-3.4)

−1.12 (−5.7-3.4)

0.2 (−4.3-4.8)

−4.8 (−9.1- -0.6)*

−3.1 (−7.2-0.9)

1.7 (−2.3-5.8)

−26.4 (−66.5-13.6)

−7.8 (−46.3-30.7)

18.6 (−20.3-57.8)

−12.9 (−56.7-30.7)

−13.5 (−55.5-28.5)

−0.5 (−43.02-41.9)