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Table 2 Percentage of IA patients and control patients with new chronic comorbid disorders after diagnosis†

From: Increased risk for chronic comorbid disorders in patients with inflammatory arthritis: a population based study

 

IA patients

Matched controls

HR crude

95% CI

HR adjusted#

95% CI

p-value

Main disease group*

       

 Diagnosis

       

Blood and blood forming organs

3%

1%

2.0

(1.5-2.6)

1.9

(1.4-2.6)

<0.001

 Anaemia§

2%

1%

2.0

(1.4-2.7)

2.0

(1.4-2.7)

<0.001

Respiratory

7%

5%

1.6

(1.3-1.9)

1.5

(1.3-1.8)

<0.001

 COPD§

4%

2%

1.8

(1.4-2.3)

1.8

(1.4-2.3)

<0.001

 Asthma (R96)

4%

3%

1.4

(1.1-1.8)

1.3

(1.0-1.7)

0.015

Neurological

8%

5%

1.5

(1.3-1.7)

1.4

(1.2-1.6)

<0.001

 Carpal tunnel syndrome (N93)

3%

2%

1.8

(1.4-2.4)

1.7

(1.3-2.3)

<0.001

 Peripheral neuritis/neuropathy (N94)

3%

2%

1.9

(1.5-2.5)

1.7

(1.3-2.2)

<0.001

Psychological

9%

7%

1.3

(1.1-1.5)

1.3

(1.1-1.4)

0.003

 Anxiety disorder§

2%

1%

1.5

(1.1-2.1)

1.4

(1.0-2.0)

0.035

 Depressive disorder (p76)

4%

3%

1.4

(1.1-1.8)

1.4

(1.1-1.7)

0.012

Cardiovascular

23%

18%

1.3

(1.2-1.4)

1.3

(1.2-1.5)

<0.001

 Phlebitis/thrombophlebitis (K94)

2%

1%

1.8

(1.3-2.4)

1.7

(1.2-2.3)

0.002

 Varicose veins of leg (K95)

3%

2%

1.4

(1.1-1.8)

1.4

(1.1-1.8)

0.009

 Hypertension§

12%

9%

1.3

(1.1-1.5)

1.3

(1.1-1.5)

0.001

 Heart failure (K77)

3%

2%

1.4

(1.1-1.9)

1.5

(1.1-2.0)

0.005

Digestive

5%

4%

1.3

(1.1-1.6)

1.3

(1.0-1.5)

0.02

Musculoskeletal b

17%

14%

1.3

(1.1-1.4)

1.3

(1.1-1.4)

<0.001

 Osteoporosis (L95)

3%

2%

1.9

(1.4-2.4)

1.9

(1.5-2.5)

<0.001

 Spinal Cord§

9%

7%

1.4

(1.2-1.6)

1.3

(1.1-1.5)

0.001

Endocrine a

10%

9%

1.1

(0.9-1.2)

1.0

(0.9-1.2)

0.514

Other

       

 Vertiginous syndrome (H82)

3%

2%

1.5

(1.2-1.9)

1.4

(1.1-1.8)

0.005

 Cancer§

5%

4%

1.3

(1.1-1.6)

1.3

(1.1-1.6)

0.004

 Eczema§

5%

4%

1.3

(1.0-1.6)

1.3

(1.0-1.6)

0.023

  1. †Patients or controls may have several chronic comorbid disorders.
  2. *Diagnoses included are listed in supplementary file. The ICPC codes within the cluster Cancer were excluded from the main groups.
  3. HR = odds ratio, CI = confidence interval.
  4. #Adjusted for age and sex.
  5. §Cluster.
  6. aGout excluded.
  7. bCluster osteoarthritis excluded.