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Table 4 Prevalence and test performance of the single item screener using the “major depressive disorder” definition of the 9-item Patient Health Questionnaire (PHQ-9) as reference standard (95% confidence interval)

From: Diagnostic utility of a one-item question to screen for depressive disorders: results from the KORA F3 study

Age group

Prevalence

Sensitivity

Specifity

ROC-area

LR+

LR-

PPV

NPV

34-44

3.8 (2.4-5.5)

75 (53.3-90.2)

92.2 (89.8-94.2)

.836 (.747-.925)

9.61 (6.73-13.7)

.271 (.136-.542)

27.3 (17–39.6)

99 (97.7-99.6)

45-54

6.2 (4.5-8.2)

86.7 (73.2-94.9)

89.9 (87.2-92.1)

.883 (.832-.935)

8.62 (6.7-11.1)

.148 (.070-.312)

36.1 (27.1-45.9)

99 (97.9-99.6)

55-64

6 (4.4-8.0)

76.1 (61.2-87.4)

84.9 (82.1-87.5)

.805 (.741-.869)

5.05 (3.98-6.41)

.282 (.168-.472)

24.5 (17.7-32.4)

98.2 (96.8-99.1)

65-74

7.9 (5.9-10.2)

86.5 (74.2-94.4)

85.4 (82.4-88.1)

.86 (.811-.909)

5.93 (4.76-7.39)

.158 (.0791-.314)

33.6 (25.7-42.2)

98.7 (97.3-99.5)

75-85

10 (7.4-14.1)

86.5 (71.2-95.5)

83.3 (78.8-87.3)

.849 (.79-.909)

5.19 (3.93-6.84)

.162 (.0717-.367)

37.6 (27.4-48.8)

98.1 (95.7-99.4)

Female

8.4 (7.1-9.8)

81.6 (74.1-87.7)

83.8 81.8-85.6)

.827 (.973-.861)

5.04 (4.38-5.8)

.219 (.154-.313)

31.5 (26.7-36.7)

98 (97.1-98.7)

Male

4.5 (3.5 -5.6)

85.3 (74.6-92.7)

91.4 (89.8-92.8)

.883 (.84-.926)

9.87 (8.13-12)

.161 (.0908-.285)

31.5 (24.9-38.8)

99.3 (98.6-99.6)

Total

6.5 (5.6-7.4)

82.8 (77–87.7)

87.5 (86.3-88.7)

.852 (.825-.879)

6.65 (5.93-7.46)

.196 (.145-.265)

31.5 (27.6-35.7)

98.7 (98.1-99.1)

  1. ROC: receiver operating characteristic; LR+: positive likelihood ratio; LR-: negative likelihood ratio; PPV: positive predictive value; NPV: negative predictive value.