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Table 3 Prevalence and test performance of the single item screener using the “depressive mood” definition of the 9-item Patient Health Questionnaire (PHQ-9) as reference standard (95% confidence interval)

From: Diagnostic utility of a one-item question to screen for depressive disorders: results from the KORA F3 study

Age group

Prevalence

Sensitivity

Specifity

ROC area

LR+

LR-

PPV

NPV

34-44

20 (17–23.3)

37.5 (29.1-46.5)

96.5 (94.5-97.9)

.67 (.627-.713)

10.6 (6.42-17.7)

.648 (.556-.742)

72.7 (60.4-83)

86 (82.9-88.8)

45-54

25 (22–27.9)

46.1 (38.7-53.7)

95.5 (93.4-97)

.708 (.67-.745)

10.2 (6.72-15.4)

.565 (.493-.647)

76.9 (67.8-84.4)

84.4 (81.3-87.2)

55-64

31 (28–34.9)

45.8 (39.4-52.4)

93.7 (91.3-95.6)

.698 (.664-.731)

7.26 (5.08-10.4)

.578 (.514-.651)

76.9 (69.1-83.6)

79 (75.6-82.2)

65-74

32 (28–35.6)

47.9 (41–54.8)

92.7 (89.9-94.9)

.703 .667-.739)

6.54 (4.58-9.35)

.562 (.493-.642)

75.4 (67.2-82.4)

79.2 (75.4-82.6)

75-85

34 (29–39.4)

52.5 (43.2-61.6)

91 (86.6-94.3)

.717 (.669-.765)

5.82 3.74-9.05)

.523 (.432-.632)

75.3 (64.7-84)

78.5 (73.1-83.3)

Female

34 (32–36.3)

48.8 (44.6-53.1)

92.3 (90.5-93.8)

.705 (.683-.728)

6.31 (5.05-7.89)

.555 (.51-.603)

76.4 (71.6-80.8)

77.8 (75.4-80.1)

Male

22 (20–23.8)

41.5 (36.1-47)

96.1 (94.8-97.1)

.688 (.661-.715

10.6 (7.76-14.4)

.809 (.555-.667)

74.5 (67.5-80.6)

85.6 (83.6-87.5)

Total

28 (26–29.6)

46.1 (42.8-49.4)

94.3 (93.2-95.2)

.702 (.685-.719)

8.04 (6.71-9.64)

.572 (.538-.608)

75.7 (71.9-79.3)

81.8 (80.3-83.3)

  1. ROC: receiver operating characteristic; LR+: positive likelihood ratio; LR-: negative likelihood ratio; PPV: positive predictive value; NPV: negative predictive value.