Table 5 Number (%) of medications pre and post IBS, AP, IBD in those with symptoms, Salford 2002-2011
Pre IBS (n = 2361) | Post IBS (n = 1603) | Pre AP (n = 3304) | Post AP (n = 10841) | Pre IBD (n = 406) | Post IBD (n = 239) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Medications† | n | % | n | % | n | % | n | % | n | % | n | % |
NICE medications | 1181 | 50.0 | 1103 | 68.8 | 1466 | 44.4 | 5314 | 49.0 | 189 | 46.6 | 135 | 56.5 |
Bulking laxatives | 169 | 7.2 | 192 | 12.0 | 185 | 5.6 | 721 | 6.7 | 19 | 4.7 | 18 | 7.5 |
Stimulant laxatives | 127 | 5.4 | 118 | 7.4 | 311 | 9.4 | 792 | 7.3 | 17 | 4.2 | 26 | 10.9 |
Faecal softeners | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
Osmotic laxatives‡ | 123 | 5.2 | 137 | 8.5 | 274 | 8.3 | 805 | 7.4 | 14 | 3.4 | 25 | 10.5 |
Antimotility drugs | 137 | 5.8 | 145 | 9.0 | 304 | 9.2 | 529 | 4.9 | 66 | 16.3 | 50 | 20.9 |
Antispasmodic drugs | 795 | 33.7 | 967 | 60.3 | 476 | 14.4 | 3165 | 29.2 | 102 | 25.1 | 64 | 26.8 |
Tricyclic antidepressants | 169 | 7.2 | 181 | 11.3 | 277 | 8.4 | 857 | 7.9 | 20 | 4.9 | 26 | 10.9 |
SSRI | 337 | 14.3 | 277 | 17.3 | 469 | 14.2 | 1467 | 13.5 | 42 | 10.3 | 37 | 15.5 |
Other antidepressants | 69 | 2.9 | 63 | 3.9 | 82 | 2.5 | 277 | 2.6 | 4 | 1.0 | 5 | 2.1 |