Table 4 Number (%) of medications pre and post IBS, AP, IBD in those with no symptoms, Salford 2002-2011
Pre IBS (n = 5367) | Post IBS (n = 6062) | Pre AP (n = 36670) | Post AP (n = 27010) | Pre IBD (n = 930) | Post IBD (n = 1143) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Medications† | n | % | n | % | n | % | n | % | n | % | n | % |
NICE medications | 1176 | 21.9 | 2974 | 49.1 | 6720 | 18.3 | 8018 | 29.7 | 191 | 19.9 | 300 | 26.2 |
Bulking laxatives | 119 | 2.2 | 437 | 7.2 | 569 | 1.6 | 840 | 3.1 | 21 | 2.2 | 32 | 2.8 |
Stimulant laxatives | 77 | 1.4 | 129 | 2.1 | 795 | 2.2 | 896 | 3.3 | 19 | 2.0 | 33 | 2.9 |
Faecal softeners | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 | 0 | 0.0 |
Osmotic laxatives‡ | 93 | 1.7 | 152 | 2.5 | 571 | 1.6 | 745 | 2.8 | 13 | 1.4 | 25 | 2.2 |
Antimotility drugs | 109 | 2.0 | 284 | 4.7 | 423 | 1.2 | 450 | 1.7 | 66 | 6.9 | 119 | 10.4 |
Antispasmodic drugs | 533 | 9.9 | 2430 | 40.1 | 1414 | 3.9 | 3870 | 14.3 | 55 | 5.7 | 85 | 7.4 |
Tricyclic antidepressants | 228 | 4.2 | 372 | 6.1 | 1647 | 4.5 | 1364 | 5.0 | 46 | 4.8 | 52 | 4.5 |
SSRI | 471 | 8.8 | 680 | 11.2 | 3061 | 8.3 | 2488 | 9.2 | 59 | 6.1 | 92 | 8.0 |
Other antidepressants | 55 | 1.0 | 84 | 1.4 | 472 | 1.3 | 383 | 1.4 | 8 | 0.8 | 10 | 0.9 |