Variable | Intervention group (N = 198 patients) | Control group (N = 206 patients) | GEE model p value |
---|---|---|---|
Male [N] (%) | 81 (40.9) | 63 (30.6) | 0.033 |
Age [years] mean (SD) | 81.4 (5.6) | 79.5 (8.7) | 0.005 |
Weight [kg] mean (SD) | 70.6 (12.5) | 71.8 (14.1) | 0.376 |
Serum creatinine [mg/dl] mean (SD) | 1.47 (0.44) | 1.52 (0.55) | 0.348 |
Estimated creatinine clearance [ml/min] mean (SD) | 38.8 (7.8) | 39.0 (8.2) | 0.733 |
Diagnosed hypertension [N] (%) | 97 (49.0) | 96 (46.6) | 0.775 |
Prescriptions per patient mean (SD) | 6.7 (3.0) | 7.1 (3.1) | 0.318 |
Prescriptions per patient requiring dose reduction mean (SD) | 1.4 (0.9) | 1.5 (1.1) | 0.124 |