A cross-validation of the provisional diagnostic instrument (PDI-4)

BMC Primary Care

Table 3 Operating characteristics of PDI-4 based diagnosis relative to diagnosis based on corresponding rating scales

		Operating Characteristics of PDI-4 Scale Using the Comparator Scale Diagnostic Cutoff
PDI-4 Scale	Comparator Scale Diagnostic Cutoff	Sensitivity (95% CI)	Specificity (95% CI)	PPV (95% CI)	NPV (95% CI)
PDI-4-GAD	HADS-A (≥ 14)	0.64 (0.54, 0.74)	0.92 (0.90, 0.93)	0.44 (0.35, 0.52)	0.96 (0.95, 0.97)
PDI-4-MDE	PHQ-9 (≥ 12)	0.69 (0.64, 0.75)	0.90 (0.88, 0.92)	0.72 (0.66, 0.77)	0.89 (0.87, 0.91)
PDI-4-ADHD	CAARS-S (≥ 28)	0.70 (0.62, 0.77)	0.87 (0.85, 0.89)	0.49 (0.42, 0.55)	0.94 (0.93, 0.96)
PDI-4-Mania	MDQ (≥ 7)	0.52 (0.46, 0.59)	0.86 (0.83, 0.88)	0.52 (0.46, 0.59)	0.86 (0.83, 0.88)

Abbreviations: ADHD = attention deficit hyperactivity disorder; CAARS-S = Conners’ Adult ADHD Rating Scale Self Report; CI = confidence interval; HADS-A = Hospital Anxiety and Depression Scale-Anxiety subscale; GAD = generalized anxiety disorder; MDE = major depressive episode; MDQ = Mood Disorder Questionnaire; NPV = negative predictive value; PDI-4 = Provisional Diagnostic Instrument; PHQ-9 = Patient Health Questionnaire for depression; PPV = positive predictive value.

ISSN: 2731-4553