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Table 3 Diagnostic value of the cardiovascular risk profile, known cardiovascular history and the clinical examination for low ABI.

From: To screen or not to screen for peripheral arterial disease in subjects aged 80 and over in primary health care: a cross-sectional analysis from the BELFRAIL study

Test Sens, % (95% CI) Spec, % (95% CI) NPV, % (95% CI) PPV, % (95% CI) Missed cases (%) Negative ABI (%)
CV risk factor*, n ≥ 1 92.9 (84.1-97.6) 12.4 (6.8-20.2) 72.2 (46.5-90.2) 41.4 (33.6-49.5) 5/70 (7.1) 92/157 (58.6)
CV morbidity*, n ≥ 1 65.7 (53.4-76.7) 48.6 (38.7-58.5) 68.0 (56.2-78.3) 46.0 (36.0-56.3) 24/70 (34.3) 54/100 (54.0)
CV morbidity*, n ≥ 3 27.1 (17.2-39.1) 92.4 (85.5-96.6) 65.5 (57.3-73.2) 70.4 (49.8-86.2) 51/70 (72.9) 8/27 (29.6)
Cardiac morbidity, n ≥ 1 60.0 (47.6-71.5) 61.0 (50.9-70.3) 69.6 (59.1-78.7) 50.6 (39.4-61.8) 28/70 (40.0) 41/83 (49.4)
Other CV morbidity, n ≥ 1 30 (19.6-42.1) 80 (71.1-87.2) 63.2 (54.4-71.4) 50.0 (34.2-65.8) 49/70 (70.0) 21/42 (50.0)
Clinical examination$ 45.7 (35.4-56.3) 79.8 (74.0-84.9) 77.7 (71.8-82.9) 48.9 (38.1-59.8) 51/94 (54.3) 45/88 (51.1)
Cardiac morbidity* (n ≥ 1) AND Clinical examination$ 35.1 (25.5-45.6) 87.0 (81.9-91.1) 76.1 (70.4-81.2) 53.2 (40.1-66.0) 61/94 (64.9) 29/62 (46.8)
  1. *Prevalence of ABI < 0.90 was 40%, $ Prevalence of ABI < 0.9 was 29.7%. ABI: ankle-brachial index; Sens: sensitivity; CI: confidence interval; Spec: specificity; NPV: negative predictive value; PPV: positive predictive value; CV: cardiovascular.