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Table 2 Baseline characteristics of study participants

From: Oral vitamin B12 for patients suspected of subtle cobalamin deficiency: a multicentre pragmatic randomised controlled trial

 

Oral B12 (N = 26)

Placebo (N = 24)

Gender (Female)

14 (53.8%)

13 (54.2%)

n (%)

  

Age

  

Mean (SD)

69.6 yrs (SD = 18.8)

68.6 yrs (SD = 18.5)

Median (range)

76 yrs (31 - 91)

75 yrs (18 - 88)

Serum B12

  

Mean (SD)

164 pM/l (SD = 24)

154 pM/l (SD = 20)

Median (range)

164 pM/l (127 - 203)

150 pM/l (126 - 191)

Serum MMA

  

Mean (SD)

0.43 μmol/l (SD = 0.25)*

0.41 μmol/l (SD = 0.24)*

Median (range)

0.32 μmol/l (0.19 - 1.1)

0.31 μmol/l (0.15 - 0.92)

MMA ≥ 0.26 μmol/l

  

n (%)

18 (83.3%)*

16 (72.7%)*

Serum HCys

  

Mean (SD)

18.3 μmol/l (SD = 6.6)*

15.0 μmol/l (SD = 5.3)*

Median (range)

18.1 μmol/l (9.8 - 31.5)

14.3 μmol/l (7.5 - 27.1)

Hematocrit

  

Mean (SD)

40.3% (SD = 4.2)

39.5% (SD = 4.6)

Median (range)

39.5% (32 - 46)

40% (27 - 47)

Mean corpuscular volume

  

Mean (SD)

91.2 fl (SD = 9.2)

92.6 fl (SD = 5.1)

Median (range)

90 fl (63 - 100)

92 fl (81 - 111)

Serum creatinine

  

Mean (SD)

96.4 μmol/l (SD = 27.9)

89.0 μmol/l (SD = 27.2)

Median (range)

86 μmol/l (60 - 160)

89 μmol/l (37 - 137)

Serum folic acid

  

Mean (SD)

16.6 nmol/l (SD = 9.1)

19.2 nmol/l (SD = 10.9)

Median (range)

16.2 nmol/l (5.6 - 45.3)

14 nmol/l (5.4 - 33)

  1. Hcys = homocysteine, MMA = methylmalonic acid, SD = standard deviation
  2. * Transport inconvenient generated missing total at random data; samples were not analysed for 2 patients in the oral B12 group and for 2 patients in the placebo group.
  3. One physician did not report results from the blood formula onto the case report form. Data were unvailable for one patient in the oral B12 group.