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Table 5 Sensitivity, specificity and NPV of cardiovascular biomarkers in relation to the working and confirmed diagnoses.

From: Diagnostic accuracy of point-of-care testing for acute coronary syndromes, heart failure and thromboembolic events in primary care: a cluster-randomised controlled trial

Biomarker

Working/Confirmed diagnosis

Sensitivity

Specificity

NPV

  

n

%

n

%

n

%

cTnT

Working ACS

11/26

42

113/121

93

113/128

88

 

Confirmed ACS

10/17

59

121/130

93

121/128

95

NT-proBNP

Working HF

33/35

94

26/35

74

26/28

93

 

Confirmed HF

31/31

100

28/39

72

28/28

100

D-dimer

Working TE

16/20

80

78/98

80

78/82

95

 

Confirmed TE

13/14

93

81/104

78

81/82

99

  1. (i) ACS, acute coronary syndromes; cTnT, cardiac troponin T; HF, heart failure; NPV, negative predictive value; NT-proBNP, N-terminal pro-brain natriuretic peptide; TE, thromboembolic events.