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Table 2 Description of studies

From: Does clinical examination aid in the diagnosis of urinary tract infections in women? A systematic review and meta-analysis

Study/Year

Design

Participants

Tests and reference

Variables measured

Prevalence UTI

Verest LFHM (14)

2000

prospective

- 292 women suspect of UTI

- age > 12 yr

- primary care

- excluded if antibiotic has been taken

- Netherlands

-dipstick

-culture

- nitrites and leukocytes in dipstick test (cut-off not defined)

- culture (UTI if ≥105 CFU/mL)

p(UTI) 58% (168/292)

Baerheim A (19)

1999

Prospective

symptoms were registered in the patient's home for three days

- 196 women with symptoms of the lower urinary tract

- age 48 yr (average)

- primary care

- Norway

- self-monitoring of symptoms thrice daily for 3 days

- dipstick test

- culture

- dysuria

- frequency

- urge

- suprapubic pain

- low back pain

- pyuria on dipstick

- culture (UTI if ≥105 CFU/mL)

p(UTI) = 46.8%

Dawborn JK (20)

1973

prospective

- 62 women with symptoms suggestive of UTI

- age 15-50 yr

- primary care

- Victoria (Australia)

- questionnaire for the register of antecedents, symptoms and signs

- culture

- history of urinary complaints

- pain on micturition

- frequency

- back pain

- anorexia

- vaginal irritation

- abundant vaginal discharge

- culture (UTI if ≥105 CFU/mL)

p(UTI) = 63% (37/59)

Fahey T (21)

2003

Prospective

- 136 women with symptoms for UTI

- age not indicated

- primary care

- United Kingdom

- asked about explicity for 11 symptoms associated with UTI

- near patient test

- culture

- frquency and dysuria

- dysuria

- fequency

- haematuria

- urgeny

- nocturia

- nauses

- vomiting

- abdominal pain

- back pain

- vaginal discharge

- leukocyte near patient test

- nitrite

- culture (UTI if ≥105 CFU/mL)

p(UTI) = 38%

Fairley KF (22)

1971

prospective

- 78 women with symptomatic micturition

- age 8-80 yr, most 30-40 yr

- primary care

- Victoria (Australia)

- symptoms and signs were registered systematically

- urine culture

- bladder catheterized depending on culture results

- frequency

- burning

- suprapubic pain

- loin pain

- temperature

- rigors

- nausea and vomiting

- haematuria (microscopy)

- culture (UTI if ≥104 bacteria/mL)

p(UTI) = 71% (55/78)

Jellheden B (23)

1996

systematic register of clinical findings from all patients

- 819 women with signs and symptoms suggesting UTI

- age over 18 yr

- primary care

- Sweden

- dipstick test

- urinoculture

-dysuria

-frequency

-suprapubic pain

-flank pain

-fever

-nitrites on dipstick

- culture (agar, UTI if ≥105 CFU/mL)

p(UTI) = 83%

Lawson DH (24)

1973

prospective

-343 women with symptomatic micturition

- age 15-55 yr

- Canada

- use of a questionnaire to register data

- urine sample

- urinoculture

- control of evolution after 14 days

- pyrexia

- loin pain

- frequency

- dysuria

- nocturia

- stress incontinence

- previous symptoms

- culture (UTI if ≥105 CFU/mL)

p(UTI) = 34.3%

Leibovici L (25)

1989

prospective

- 266 women with dysuria

- 17 to 25 years old

- primary care

- Israel

- clinical interview and examination followed a check-list

- urine sample taken for dipstick and culture

- sexual activity

- vaginal discharge

- duration of symptoms

- pyuria (sediment)

- hematuria (sediment)

- culture (agar, UTI if ≥105 CFU/mL)

p(UTI) = 55.3%

Medina-Bombardó D (26)

2003

prospective

- 343 women with incident urinary symptoms

- Median age 44 years old, (range 15-90)

- Primary care

- Spain

- clinical systematically interview and clinical exam by check-list

- urine reactive strip test

- urinoculture

- urinary symptoms: freqúency, burning, tenesmus, urgency, painfou voiding, difficult, diurnal and or nocturnal incontinence and combinations two of them.

- medical history: urinary tract infections, sexual activity, vulvovaginitys, urolithiasis, diabetes mellitus, urinary catheterization

- sings: lower abdominal pain, positive fist percussion, genital erythema, fever

- accompanying symptoms: lower abdominal discomfort, general malaise, genital discomfort, dyspareunia, cold chills, uncreased vaginal discharge, perineal discomfort.

- reactive strip test: pyuria, nitrite

- culture (agar, UTI if ≥105 CFU/mL)

p(UTI) = 48.4%

Nazareth I (27)

1993

prospective

- 61 women presenting with symptoms on urination (frequency or dysuria)

- 16-45 years old

- primary care

- no antibiotic treatment

- United Kingdom

- data on symptoms, signs and clinical exam were collected by the physician using a questionnaire with open questions

- urine sample for culture

- dysuria

- frequency

- urgency

- vaginal symptoms

- abdominal symptoms

- back pain

- haematuria

- fever

- culture (≥105 CFU/L)

p(UTI) = 28%

Osterberg E (28)

1996

prospective

- 217 women with dysuria and/or urgency/frequency

- age 15-35 yr

- primary care

- Sweden

- questionnaire on symptoms

- dipstick

- culture on "Dipslide"

- dysuria and urgency/frequency

- nitrites on dipstick

- positive granulocyte esterase (≥1)

- culture (UTI if ≥105 CFU/mL)

p(UTI) = 52%

  1. UTI urinary tract infection; CFU/mL Colony Forming Units/milliliter sample; p(UTI) prevalence of UTI