Sex, n (%)
|
Female
|
58 (55.2%)
|
269 (76.4%)
|
<0.001
|
Age
|
Mean ± SD (n)
|
51.1 ± 14.7 (100)
|
39.9 ± 11.5 (340)
|
<0.001
|
CGI-Severity a
|
Mean ± SD (n)
|
4.4 ± 0.8 (105)
|
5.1 ± 1.1 (344)
|
<0.001
|
Medications prescribed, n (%)
|
SSRIs
|
66 (88.0%)
|
275 (93.2%)
|
0.149
|
|
TCAs
|
0 (0.0%)
|
5 (1.7%)
|
0.588
|
|
Venlafaxine
|
3 (4.0%)
|
6 (2.0%)
|
0.395
|
|
Mirtazapine
|
7 (9.3%)
|
8 (2.7%)
|
0.017
|
|
Other ADs
|
0 (0.0%)
|
20 (6.8%)
|
0.018
|
|
Anxiolytics
|
5 (6.7%)
|
52 (17.6%)
|
0.019
|
|
Hypnotics
|
11 (14.7%)
|
2 (0.7%)
|
<0.001
|
|
Analgesics
|
10 (13.3%)
|
15 (5.1%)
|
0.018
|
Presenting symptoms (psychological), n (%) a
|
Depression
|
70 (65.4%)
|
267 (75.6%)
|
0.046
|
|
Anxiety
|
55 (51.4%)
|
188 (53.3%)
|
0.742
|
|
Sleep
|
55 (51.4%)
|
201 (56.9%)
|
0.320
|
Presenting symptoms (physical), n (%) a
|
Fatigue
|
47 (43.9%)
|
200 (56.7%)
|
0.027
|
|
Pain
|
40 (37.4%)
|
209 (59.2%)
|
<0.001
|
|
Gastro-intestinal
|
21 (19.6%)
|
150 (42.5%)
|
<0.001
|
|
Cardiovascular
|
8 (7.5%)
|
86 (24.4%)
|
<0.001
|
|
CNS
|
29 (27.1%)
|
194 (55.0%)
|
<0.001
|
Number of psychological symptoms a
|
Mean ± SD (n)
|
1.7 ± 0.9 (107)
|
1.9 ± 0.9 (353)
|
0.067
|
Number of physical symptoms a
|
Mean ± SD (n)
|
1.4 ± 1.1 (107)
|
2.4 ± 1.3 (353)
|
<0.001
|
HADS-Depression b
|
Mean ± SD (n)
|
10.3 ± 4.2 (99)
|
12.8 ± 4.5 (335)
|
<0.001
|
HADS-Anxiety b
|
Mean ± SD (n)
|
12.9 ± 4.0 (99)
|
12.6 ± 4.0 (335)
|
0.577
|
Prominent symptoms-Depression b
|
Mean ± SD (n)
|
5.9 ± 2.2 (97)
|
6.8 ± 2.6 (342)
|
0.005
|
Prominent symptoms-Anxiety b
|
Mean ± SD (n)
|
5.7 ± 2.4 (101)
|
6.1 ± 2.8 (339)
|
0.259
|
Prominent symptoms-Stress b
|
Mean ± SD (n)
|
6.2 ± 2.6 (101)
|
6.9 ± 2.5 (341)
|
0.010
|
Prominent symptoms-Sleep b
|
Mean ± SD (n)
|
5.9 ± 2.9 (101)
|
6.4 ± 2.9 (341)
|
0.158
|
Prominent symptoms-Pain b
|
Mean ± SD (n)
|
4.8 ± 3.1 (101)
|
6.2 ± 2.8 (342)
|
<0.001
|
SDS-Work b
|
Mean ± SD (n)
|
6.0 ± 3.2 (98)
|
6.0 ± 2.7 (332)
|
0.873
|
SDS-Social b
|
Mean ± SD (n)
|
6.9 ± 2.5 (102)
|
6.8 ± 2.5 (342)
|
0.564
|
SDS-Family b
|
Mean ± SD (n)
|
6.6 ± 2.5 (102)
|
6.5 ± 2.6 (342)
|
0.882
|