Table 1 Demographic and clinical characteristics at baseline
Characteristic | Diabetic peripheral neuropathy | Postherpetic neuralgia | ||||||
|---|---|---|---|---|---|---|---|---|
| Â | Placebo (n = 558) | Pregabalin 150 mg/day (n = 176) | Pregabalin 300 mg/day (n = 266) | Pregabalin 600 mg/day (n = 513) | Placebo (n = 363) | Pregabalin 150 mg/day (n = 251) | Pregabalin 300 mg/day (n = 230) | Pregabalin 600 mg/day (n = 159) |
Male, n (%) | 308 (55.2) | 110 (62.5) | 144 (54.1) | 309 (60.2) | 180 (49.6) | 117 (46.6) | 103 (44.8) | 76 (47.8) |
   Age, n (%) |  |  |  |  |  |  |  |  |
18-64 y | 366 (65.6) | 127 (72.2) | 182 (68.4) | 344 (67.1) | 68 (18.7) | 57 (22.7) | 45 (19.6) | 47 (29.5) |
65-74 y | 158 (28.3) | 39 (22.2) | 62 (23.3) | 139 (27.1) | 143 (39.4) | 92 (36.6) | 64 (27.8) | 69 (43.4) |
≥75 y | 34 (6.1) | 10 (5.7) | 22 (8.3) | 30 (5.8) | 152 (41.9) | 102 (40.6) | 121 (52.6) | 43 (27.0) |
   Race |  |  |  |  |  |  |  |  |
White | 496 (88.9) | 167 (94.9) | 243 (91.4) | 460 (89.7) | 354 (97.5) | 244 (97.6) | 226 (99.1) | 154 (96.9) |
Black | 28 (5.0) | 3 (1.7) | 10 (3.8) | 22 (4.3) | 2 (0.5) | 4 (1.6) | 2 (0.9) | 1 (0.6) |
Hispanic | 24 (4.3) | 2 (1.1) | 7 (2.6) | 20 (3.9) | 4 (1.1) | 2 (0.8) | 1 (0.4) | 4 (2.5) |
Asian or Pacific Islander | 2 (0.4) | 2 (1.1) | 3 (1.1) | 5 (1.0) | 2 (0.5) | 1 (0.4) | 0 | 0 |
Alaskan or Native American | 1 (0.2) | 0 | 1 (0.4) | 0 | 0 | 0 | 0 | 0 |
Other | 7 (1.3) | 2 (1.1) | 2 (0.8) | 6 (1.2) | 1 (0.3) | 0 | 1 (0.4) | 0 |
   Weight, kg, mean (SD) | 92.6 (20.6) | 91.1 (17.8) | 93.6 (20.1) | 93.1 (19.8) | 74.7 (15.7) | 73.9 (15.6) | 69.8 (13.6) | 77.8 (13.9) |
   Height, cm, mean (SD) | 170.8 (10.1) | 172.3 (10.2) | 171.4 (10.1) | 171.2 (9.9) | 167.0 (9.9) | 165.5 (9.8) | 165.3 (10.5) | 166.3 (11.1) |
   CLcr, mL/min |  |  |  |  |  |  |  |  |
Mean (SD) | 101.9 (37.3) | 101.0 (33.0) | 101.7 (36.7) | 98.5 (30.3) | 69.9 (26.5) | 68.7 (24.3) | 63.2 (24.3) | 84.8 (22.3) |
N | 554 | 175 | 265 | 511 | 362 | 250 | 230 | 156 |
   Baseline paina |  |  |  |  |  |  |  |  |
Mean (SD) | 6.5 (1.6) | 6.3 (1.4) | 6.4 (1.4) | 6.6 (1.6) | 6.6 (1.5) | 6.6 (1.6) | 6.8 (1.5) | 6.5 (1.5) |
N | 550 | 175 | 265 | 508 | 361 | 250 | 230 | 154 |
   Baseline sleepb |  |  |  |  |  |  |  |  |
Mean (SD) | 5.3 (2.4) | 5.1 (2.4) | 5.6 (2.2) | 5.4 (2.6) | 4.6 (2.7) | 4.5 (2.5) | 4.8 (2.6) | 4.8 (2.4) |
N | 549 | 175 | 265 | 508 | 361 | 250 | 230 | 154 |